New mechanism for long-term memory formation discovered

UC Irvine neurobiologists have found a novel molecular mechanism that helps trigger the formation of long-term memory. The researchers believe the discovery of this mechanism adds another piece to the puzzle in the ongoing effort to uncover the mysteries of memory and, potentially, certain intellectual disabilities.

molecular dynamics simulation of p53 and stictic acid

Sequestration casts shadow over research labs

Recent UCI discovery related to cancer treatment is the type of work endangered

Bert Semler

Going viral

UCI microbiologist Bert Semler seeks to stop certain viruses from replicating, changing the way we fight the common cold and other illnesses

UCI team finds new target for treating wide spectrum of cancers

UC Irvine biologists, chemists and computer scientists have identified an elusive pocket on the surface of the p53 protein that can be targeted by cancer-fighting drugs. The finding heralds a new treatment approach, as mutant forms of this protein are implicated in nearly 40 percent of diagnosed cases of cancer, which kills more than half a million Americans each year.

UC Irvine study of leaping toads reveals muscle-protecting mechanism

UC Irvine biology Emanuel Azizi found that toads possess a neuromuscular response that’s specific to the intensity of a landing – a mechanism that protects muscles from injury upon impact. The findings have implications for improving rehabilitation programs for people with neuromuscular deficiencies.

State board awards $2.833 million for desert research center improvements

The California Wildlife Conservation Board has awarded $2.833 million in Proposition 84 funds for new construction at UC Irvine’s Steele/Burnand Anza-Borrego Desert Research Center in Borrego Springs.

Ulcer bug's Achilles' heel revealed in UCI-led study

Irvine, Calif., Dec. 11, 2012 — Research led by a UC Irvine structural biologist has revealed a potential new way to attack common stomach bacteria that cause ulcers and significantly increase the odds of developing stomach cancer. Hartmut “Hudel” Luecke, professor of molecular biology & biochemistry, and colleagues focused on the bacterium Helicobacter pylori, which […]

UCI's cloned redwoods rooted in research

Grove fell short of great expectations but has proven valuable in Earth system science studies

Highlights of 2012 at UCI

Year brings scientific advances, national accolades, international outreach, student achievement and loss of campus stalwarts

Bruce Blumberg part of team behind new safety system for chemical design

A groundbreaking study involving Bruce Blumberg, UCI professor of developmental & cell biology, outlines a safety testing system that helps chemists design inherently safer chemicals and processes.