A groundbreaking study involving Bruce Blumberg, UCI professor of developmental & cell biology, outlines a safety testing system that helps chemists design inherently safer chemicals and processes. Resulting from a cross-disciplinary collaboration among scientists, the innovative TiPED (Tiered Protocol for Endocrine Disruption) testing system provides information for making chemicals and consumer products safer. It can be applied at different phases of the chemical design process and can steer companies away from inadvertently creating harmful products, such as BPA or DDT. The study appears online in Green Chemistry. The collaboration that led to this paper – comprising 23 biologists, green chemists and others from North America and Europe – began with a conference on green chemistry held at UCI in 2007.