KEYWORD

RNA

UC Irvine-led research team leverages power of ribosomes to develop chemical libraries

Transformative technique replaces manual process, accelerating discovery of new drugs

Vivek Swarup

UC Irvine neuroscientists develop ‘meta-cell’ to move Alzheimer’s fight forward

New process reveals single-cell secrets for novel therapeutic targets

John Chaput

UCI scientists develop gene silencing DNA enzyme that can target a single molecule

Breakthrough holds promise for disease treatments, precision medicine

Three UCI scientists win NIH Director’s New Innovator Awards

High-Risk, High-Reward grants will support biomedical research projects

John Chaput

UCI-developed COVID-19 test detects, identifies specific variants with 100% accuracy

RNA-based method advances personalized medicine for improved patient care

UCI team develops simplified, faster process for detection of viral RNA in saliva samples

UCI researchers have originated a simplified, faster clinical sample testing method to detect genetic material, including viral RNA. Their findings were recently published in the journal Scientific Reports. “We showed that a saliva sample withdrawn using a simple microbiological loop can be directly analyzed in a single collection tube, using common and precise DNA amplification […]

Ali Mortazavi

How life works is his life’s work

UCI professor of developmental and cell biology seeks answers to how genes are regulated

Gorodetsky Wins NIH Director’s New Innovator Award

Grant supports novel cell-to-cell communication technology

UCI team gets $1 million Keck Foundation grant to develop tools for RNA observation

A multidisciplinary team of UCI professors has received a $1 million grant from the W.M. Keck Foundation to develop new molecular tools to identify ribonucleic acids essential in learning and memory formation. “Our project involves building luminescent RNA molecules, allowing us to observe their position and activity in the brain of a living, learning mouse,” […]

UCI lands $1 million Keck Foundation grant to develop new RNA tools

Two UCI researchers have received a $1 million grant from the prestigious W.M. Keck Foundation to develop new technologies to study the dynamic properties of key RNA modifications. The grant goes to principal investigator Robert Spitale, assistant professor of pharmaceutical sciences, and co-investigator John Chaput, professor of pharmaceutical sciences, chemistry and molecular biology & biochemistry. […]