KEYWORD

DNA

Shahrdad Lotfipour

UC Irvine to lead study of how DNA genetic variations might influence nicotine addiction

Findings may improve prevention and treatment strategies for smoking, vaping habits

Genomics team: Wei Li (left), Ya Cui, Wenbin Ye and Jason Sheng Li.

UC Irvine-led research team builds first tandem repeat expansions genetic reference maps

Tool gives potential to expand insight into diseases, neurological disorders and cancers

Three men.

UC Irvine-led research team discovers role of key enzymes that drive cancer mutations

APOBEC3A and APOBEC3B offer potential new targets for intervention strategies

UC Irvine-led research team leverages power of ribosomes to develop chemical libraries

Transformative technique replaces manual process, accelerating discovery of new drugs

Stacy Copp standing in a laboratory.

Discovery through mentorship

UCI materials science and engineering project gives student researchers opportunities to excel

Pharmaceutical Sciences professor John Chaput holds a vial of synthetic DNA

X Marks the Spot

Three questions with professor of pharmaceutical sciences John Chaput, who discusses using synthetic genetics in drug discovery

Three UCI scientists win NIH Director’s New Innovator Awards

High-Risk, High-Reward grants will support biomedical research projects

UCI biologists track DNA “parasites” in the hunt for disease treatments

Study uncovers key insights into little-understood phenomenon

UCI team develops simplified, faster process for detection of viral RNA in saliva samples

UCI researchers have originated a simplified, faster clinical sample testing method to detect genetic material, including viral RNA. Their findings were recently published in the journal Scientific Reports. “We showed that a saliva sample withdrawn using a simple microbiological loop can be directly analyzed in a single collection tube, using common and precise DNA amplification […]

Ali Mortazavi

How life works is his life’s work

UCI professor of developmental and cell biology seeks answers to how genes are regulated