KEYWORD

DNA

Rémi Buisson (center), UC Irvine associate professor of biological chemistry. He’s flanked by postdoctoral fellow Elodie Bournique and graduate student Ambrocio Sanchez.

New mechanism discovered that triggers immune response in cells with damaged DNA

Finding by UC Irvine researchers could lead to more effective cancer treatments

Dorota Skowronska-Krawczyk, UC Irvine associate professor of physiology and biophysics.

UC Irvine-co-led study finds DNA damage is key factor in age-related macular degeneration

Targeting specific retinal cell types could lead to treatments that slow or stop progression

John Chaput

UC Irvine-led team engineers new enzyme to produce synthetic genetic material

Discovery advances development of new therapeutic options for cancer and other diseases

Shahrdad Lotfipour

UC Irvine to lead study of how DNA genetic variations might influence nicotine addiction

Findings may improve prevention and treatment strategies for smoking, vaping habits

Genomics team: Wei Li (left), Ya Cui, Wenbin Ye and Jason Sheng Li.

UC Irvine-led research team builds first tandem repeat expansions genetic reference maps

Tool gives potential to expand insight into diseases, neurological disorders and cancers

Three men.

UC Irvine-led research team discovers role of key enzymes that drive cancer mutations

APOBEC3A and APOBEC3B offer potential new targets for intervention strategies

UC Irvine-led research team leverages power of ribosomes to develop chemical libraries

Transformative technique replaces manual process, accelerating discovery of new drugs

Stacy Copp standing in a laboratory.

Discovery through mentorship

UCI materials science and engineering project gives student researchers opportunities to excel

Pharmaceutical Sciences professor John Chaput holds a vial of synthetic DNA

X Marks the Spot

Three questions with professor of pharmaceutical sciences John Chaput, who discusses using synthetic genetics in drug discovery

Three UCI scientists win NIH Director’s New Innovator Awards

High-Risk, High-Reward grants will support biomedical research projects