Shedding (fluorescent) light on Ebola

A fluorescent green limb pokes outward from a cell wall under a high-powered microscope. The filament is loaded with VP40, an essential protein in the Ebola virus. The microscope is capturing it budding out in real time. It’s followed by another and another. Those green protrusions may be the means by which the deadly virus […]

Michelle Digman

Shedding (fluorescent) light on Ebola

UCI team uses novel technique to track key protein in deadly virus

Strict genomic partitioning by biological clock separates key metabolic functions

Irvine, Calif., July 31, 2014 — Much of the liver’s metabolic function is governed by circadian rhythms – our own body clock – and UC Irvine researchers have now found two independent mechanisms by which this occurs. The study, published online today in Cell, reveals new information about the body clock’s sway over metabolism and […]

Dr. Xiaolin Zi

Can kava cure cancer?

UC Irvine study of plant compound’s effectiveness against bladder malignancies has yielded promising results

Gene Tsudik

You’ve been hacked

With computer ‘break-ins’ growing in sophistication and number, UC Irvine researchers work to foil future attacks

Bert Semler

Going viral

UCI microbiologist Bert Semler seeks to stop certain viruses from replicating, changing the way we fight the common cold and other illnesses

UCI team finds new target for treating wide spectrum of cancers

UC Irvine biologists, chemists and computer scientists have identified an elusive pocket on the surface of the p53 protein that can be targeted by cancer-fighting drugs. The finding heralds a new treatment approach, as mutant forms of this protein are implicated in nearly 40 percent of diagnosed cases of cancer, which kills more than half a million Americans each year.

Gene Tsudik with the GenoDroid app

Gene genie

UCI smartphone app permits secure storage, testing of DNA data

UCI app safely stores DNA on smartphones

UC Irvine computer scientists have created an app that could allow an individual to securely store and use his or her own DNA on a smartphone. GenoDroid, they said, could potentially be used for paternity and common-ancestry tests, customized cancer-fighting drugs and more.

Chronic kidney disease alters intestinal microbial flora

UC Irvine study patients with renal failure experienced changes the composition of intestinal bacterial microbes that are crucial to staving off disease-causing pathogens and maintaining micronutrient balance.