Research

T regulatory cells (green with red nuclei) interact with antigen-presenting cells (magenta) in a tumor (blue). The Treg cell on top is activated (green fluorescence in the nucleus), while the one at the bottom is not (green fluorescence outside the nucleus). Activation of Treg cells promotes tumor growth.

UCI-led study finds that cancer immunotherapy may self-limit its efficacy

Common tumor inhibitor drug triggers favorable and unfavorable immune effects

Climate change is driving plant die-offs in Southern California, UCI study finds

Loss of vegetation cover is most stark in desert ecosystems already on edge of habitability

Jean Ho, postdoc, and psychological science professor Daniel Nation photo: Steve Zylius/UCI

UCI-led meta-analysis identifies hypertension medications that help ward off memory loss

People taking drugs that cross the blood-brain barrier experienced less cognitive decline

UCI-led study links age of at-risk individuals to much higher COVID-19 hospitalization rate

Age increases the likelihood of hospitalization and poor outcomes for COVID-19 patients with such preexisting conditions as heart disease, high blood pressure, high cholesterol, asthma, kidney disease and diabetes, according to a recent study led by UCI researchers. An analysis of the UC COVID Research Data Set – which contains SARS-CoV-2 testing results and COVID-19 […]

Street scene on Broadway in Los Angeles

What's next: The ongoing urban exodus

Remote worker migration will depress home prices in big cities and raise them in suburbs, says UCI economist

UCI researchers win funding to shed light on interactions between metabolism, immunity

The Paul G. Allen Frontiers Group has named two UCI researchers as Allen Distinguished Investigators. Michelle Digman, associate professor of biomedical engineering, and Jennifer Prescher, professor of chemistry, were among 10 academic experts chosen this year to explore the relationship between metabolism and the human immune system. The UCI scientists were made co-principal investigators on […]

Jonathan Lakey (right), UCI professor of surgery and biomedical engineering, and Reza Mohammadi, who earned a doctorate in materials science and engineering at UCI

UCI-led team develops transplant biomaterial that doesn't trigger immune response

Based on stem cell technology, platform can offer long-term treatment for Type 1 diabetes

Pharmacists play big role in vaccination rates, acceptability in Asia-Pacific area, study finds

Pharmacists improve vaccination acceptability and rates in the Asia-Pacific region, according to a recent study published online in the Journal of the American Pharmacists Association. Research team members from UCI included John Szeto, who earned a bachelor’s degree in public health sciences in 2020; Anhthai Nguyen, a graduate student in human-computer interaction & design; and […]

Chao family gifts to UCI Health for cancer care top $50 million

Latest donation will name cancer center at new UCI Medical Center in Irvine

Stock photo, graduation cap and tassle

Lifting Prisoners Into a Brighter Future

UCI launches the UC system’s first B.A. program for incarcerated individuals