UCI News

Which is better for developing immunity: COVID-19 vaccine or natural infection?

Orange County Register, April 28, 2021

April 28, 2021

Which is better for developing immunity: COVID-19 vaccine or natural infection?

Debate has raged over which provides better protection against COVID-19 — natural infection or vaccine injection? A large-scale study by UC Irvine researchers may definitively settle this debate. They found that, yes, natural infection provides protection, but mRNA vaccines like Pfizer and Moderna kick natural immunity’s butt in protecting against COVID-19. … “This is a pretty spectacular thing,” said Philip L. Felgner, director of UC Irvine’s Vaccine Research and Development Center and Protein Microarray Laboratory and Training Facility, who was one of the researchers. “It’s not just doing something for a relatively small group of patients with uncommon disease — here we’re talking about saving the whole world.”