Day: April 15, 2016

Too much ‘noise’ can affect brain development, UCI study finds

Using cutting-edge imaging technology, UCI biologists have determined that uncontrolled fluctuations (known as “noise”) in the concentration of the vitamin A derivative retinoic acid can lead to disruptions in brain organization during development. Identifying how a cell responds to a signal made by another cell, despite the level of noise present, may improve our understanding […]

Leslie Thompson

UCI team finds method to reduce accumulation of damaging Huntington’s disease protein

A study appearing April 14 in the journal Neuron suggests there may be a new way to change the damaging course of Huntington disease. University of California, Irvine neurobiologists Leslie Thompson and Joseph Ochaba and their colleagues from UCI and from Children’s Hospital of Philadelphia have shown that reducing the aberrant accumulation of a particular form of the […]