Compounds created to combat Alzheimer’s disease, sleep disorders and other neurological ailments reverse Huntington’s disease-related memory loss, according to a UC Irvine study. In tests on mice with HD, neurobiologists Gary Lynch (pictured), Danielle Simmons and colleagues found that a very mild ampakine treatment produced dramatic increases in the brain’s chemical processes for creating and storing memories. The study points to the potential of ampakine-based drugs – which Lynch helped discover and are already used in Alzheimer disease clinical trials – as a treatment for people with HD, a rare and fatal neurological disease. Study results appear in the early online edition of the Proceedings of the National Academy of Sciences.
Ampakine treatment reverses memory loss in Huntington's disease
Compounds created to combat Alzheimer's disease, sleep disorders and other neurological ailments reverse Huntington's disease-related memory loss, according to a…
March 5, 2009