UCI News

Studies find cell defects related to multiple sclerosis

In immunology studies related to multiple sclerosis, Dr. Michael Demetriou and his UC Irvine research colleagues found that defects on…

September 24, 2007
Studies find cell defects related to multiple sclerosis

In immunology studies related to multiple sclerosis, Dr. Michael Demetriou and his UC Irvine research colleagues found that defects on cell-surface sugars may promote the short-term inflammation and long-term neurodegeneration that occurs in the central nervous system of multiple sclerosis patients. The findings, published in the Journal of Biological Chemistry, also suggest a dietary supplement similar to glucosamine may be useful as an oral therapy to correct these defects and to treat both the short-term and the long-term symptoms of the disease. Pictured: Demetriou (center), assistant professor of neurology, and microbiology and molecular genetics, with Ani Grigorian (left) and Sung-Uk Lee (right).