UCI researchers discover cause, develop pharmacological treatment for reducing retinitis pigmentosa vision loss

Inhibiting ceramide accumulation in retina protects photoreceptors, improves vision

Stem cell therapy for retinitis pigmentosa found safe, well-tolerated in first-stage clinical trial

Sue & Bill Gross Stem Cell Research Center researchers have reported that a therapy they created to cure retinitis pigmentosa is safe and well-tolerated, with no immunological issues, by the first group of patients enrolled in an ongoing phase I/II clinical trial. Led by the regenerative medicine company jCyte, the trial has successfully undergone four […]

Dr. Henry Klassen

UCI-led team begins first clinical trial of stem cell-based retinitis pigmentosa treatment

Participants are sought for safety study on the use of retinal progenitors in the eye

Unlocking stem cells’ potential to cure eye disease a reality

Dr. Henry Klassen’s stem cell-based treatment to repair the retina is now in a clinical trial, offering new hope for people suffering from retinitis pigmentosa

Professor Henry Klassen

FDA greenlights UCI clinical trial of treatment for blinding disease

A first-of-its-kind stem cell-based treatment for retinitis pigmentosa developed by UC Irvine’s Dr. Henry Klassen, Dr. Jing Yang and colleagues has received consent from the U.S. Food & Drug Administration for use in a clinical trial.

Arnold and Mabel Beckman Foundation awards UCI’s Gavin Herbert Eye Institute $3 million for retinal degeneration research

The Gavin Herbert Eye Institute, which is part of UC Irvine Health, has been awarded a $3 million grant from the Arnold and Mabel Beckman Foundation for fellowships and instruments that advance research to prevent blindness caused by such diseases as age-related macular degeneration and retinitis pigmentosa.

Dr. Henry Klassen

Unlocking stem cells’ potential to cure eye disease

Dr. Henry Klassen is discovering new ways to use stem cells to repair the retina, offering new hope for people suffering from retinitis pigmentosa and macular degeneration.

UCI stem cell researchers to receive $9.35 million in state funding

The California Institute for Regenerative Medicine grants awarded to Dr. Henry Klassen, Leslie M. Thompson, Brian Cummings and Aileen Anderson will support early stage translational research and help create stem cell treatments for retinitis pigmentosa, Huntington’s disease and traumatic brain injury.

Baruch D. Kupperman, director of the Gavin Herbert Eye Institute

A decade of visionary achievement

UCI’s Gavin Herbert Eye Institute celebrates its 10th anniversary

UCI researchers reveal molecular mechanisms underlying mutations within the eye that lead to blindness

Understanding the key structural determinants of a highly specialized membrane in the eye could lead to new treatments, even a cure