Are COVID-19 booster shots variant-specific?

Philip Felgner, PhD, [professor of public health and] the director of the University of California, Irvine Vaccine Research and Development Center, tells Verywell that boosters will be “exactly the same” as what vaccinated people got the first time around. … While the boosters are more of the same, we may see updated COVID vaccines in the future. “The technology is very agile,” says Felgner. “And they will be able to change it or modify it and then make the next generation version as the virus mutates.”