UCI commentary expands understanding of how transplanted stem cells address disease

UCI scholars Zachary W. Wagoner, a graduate student researcher in cellular & molecular biosciences, and Weian Zhao, professor of pharmaceutical sciences, have identified a new mechanism by which transplanted stem cells treat disease. Their findings are contrary to the long-standing conventional wisdom that diseased tissue is repaired through stem cells differentiating into new cells or […]

Unlocking stem cells’ potential to cure eye disease a reality

Dr. Henry Klassen’s stem cell-based treatment to repair the retina is now in a clinical trial, offering new hope for people suffering from retinitis pigmentosa

Charles Limoli

Human neural stem cells restore cognitive functions impaired by chemotherapy

UCI study reveals how they alleviate ‘chemobrain’ after cancer treatments

Bone marrow stem cells show promise in stroke treatment, UCI team finds

Irvine, Calif., April 9, 2014 — Stem cells culled from bone marrow may prove beneficial in stroke recovery, scientists at UC Irvine’s Sue & Bill Gross Stem Cell Research Center have learned. In an analysis of published research, neurologist Dr. Steven Cramer and biomedical engineer Weian Zhao identified 46 studies that examined the use of […]

Spinal cord injury patients report regained sensation in human neural stem cells clinical trial

Swiss doctors with the world’s first clinical trial using human neural stem cells to treat chronic thoracic spinal cord injury report that two patients have regained some ability to feel touch and heat.

Human model of Huntington’s disease created from skin’s stem cells

An international consortium of Huntington’s disease experts, including several from the Sue & Bill Gross Stem Cell Research Center at UC Irvine, has generated a human model of the deadly inherited disorder directly from the skin cells of affected patients. The re-created neurons, which live in a petri dish, will help researchers better understand what […]

Researchers Aileen Anderson and Brian Cummings

Science, stem cells and serendipity

Serendipity has played a great part in the careers and personal lives of Aileen Anderson and Brian Cummings, the UC Irvine husband-and-wife team that has helped move stem cell therapy for spinal cord injury a giant step forward. They met as undergraduates at the University of Illinois at Urbana-Champaign. Cummings would visit his then-girlfriend in her dorm, and […]

Stem cells restore cognitive abilities impaired by brain cancer treatment

UCI study by radiology oncologist Charles Limoli suggests transplantation of human neural stem cells can alleviate side effects of radiotherapy.

Dr. Henry Klassen

Unlocking stem cells’ potential to cure eye disease

Dr. Henry Klassen is discovering new ways to use stem cells to repair the retina, offering new hope for people suffering from retinitis pigmentosa and macular degeneration.

Human neural stem cells restore motor function in mice with chronic spinal cord injury.

A UC Irvine study is the first to demonstrate that human neural stem cells can restore mobility in cases of chronic spinal cord injury, suggesting the prospect of treating a much broader population of patients.