Frank M. LaFerla

UCImpact: Alzheimer’s disease

UC Irvine’s impact on Alzheimer’s research is acknowledged on World Alzheimer’s Day.

Frank LaFerla and Mathew Blurton-Jones

Neural stem cells offer potential treatment for Alzheimer’s disease

UC Irvine scientists have shown for the first time that neural stem cells can rescue memory in mice with advanced Alzheimer’s disease, raising hopes of a potential treatment for the leading cause of elderly dementia that afflicts 5.3 million people in the U.S.

Andrea Tenner

Drug rescues memory lost to Alzheimer’s disease

A drug similar to one used in clinical trials for treatment of rheumatoid arthritis and psoriasis has been found to rescue memory in mice exhibiting Alzheimer’s symptoms. This discovery by UC Irvine scientists offers hope for a new treatment for early stage Alzheimer’s.

UCI Podcast Indicator

UCI Podcast: The latest on Alzheimer’s disease

UCI MIND’s Dr. Joshua Grill talks about two new drugs and a whole lot more

A big Alzheimer’s drug study is proceeding cautiously, despite the pandemic

NPR, Oct. 20, 2020 (Audio)

UCI MIND gets grant to identify compounds that reduce brain damage seen in Alzheimer’s

The UCI Institute for Memory Impairments and Neurological Disorders has been awarded a $500,000 grant from the Orange County Community Foundation’s S.L. Gimbel Foundation Fund. The money will support the testing of 1,200+ FDA-approved compounds to gauge their effectiveness in preventing microglia from destroying brain synapses. Such damage “is seen frequently in patients with Alzheimer’s […]

UCI neuroscientist Zhiqun Tan

Alzheimer’s lesions found in the retina

UC Irvine neuroscientists have found that retinas in mice genetically altered to have Alzheimer’s undergo changes similar to those that occur in the brain – most notably the accumulation of amyloid plaque lesions.

Linda Scheck

Alzheimer’s art creates lasting memories

Nine paintings created through an Alzheimer’s Association program called Memories in the Making are on display at UCI MIND.

Ampakine treatment reverses memory loss in Huntington's disease

Compounds created to combat Alzheimer’s disease, sleep disorders and other neurological ailments reverse Huntington’s disease-related memory loss, according to a…

Evaluating forgetfulness

UCI’s Memory Assessment Clinic is the only outpatient facility in Orange County providing comprehensive services focused solely on the early identification of Alzheimer’s disease and related dementias.